How would you redesign this so it is easier to follow along with the pathways that are interacting?
- The arrow means that thing goes and binds to that other thing.
- The | means it interferes with that thing.
Could you lay these out in a grid of some sort, or even a vertical list, and just link them together? Maybe you highlight one object at a time, see its connections (as you hover over it), and move around like that? Press a special key to see all interactions at once (assuming vertical list).
I just think these diagrams are almost impossible to read at this level of complexity. This is a biological cell, the Insulin Receptor Signaling Pathway (part of it at least).