Context is the king. It would be good to know more about what the page is about and what these buttons intend to do. But, here are few generally valid, insights into CTA(buttons) design/ux.
1) Ideally, there should be one main call to action, per task. Good read here: https://uxmag.com/articles/usability-tip-one-main-call-to-action-item-per-task
2) Use visual weight to differentiate b/w the buttons. To help improve accessibility, try to mix visual weight with things like a button and a link, rather than two buttons etc. Link standing for an action that is less important. Good read here: http://uxmovement.com/buttons/visual-weight-of-primary-and-secondary-action-buttons/ & http://www.lukew.com/ff/entry.asp?571
3) Use appropriate labels to make easy for the user to distinguish what they intend to do, and also think about their placement and order. For example, "Back button" makes more sense to be placed left of the page.
So as you see, in general, use 1) and 2) to good use if possible. If not, focus on good labeling is what I would suggest.