Generally speaking, negative space is not used as dramatically in UX as it is used in graphic design. Graphic design uses it to guide the eye and focus attention on certain things and this can often show up to be a very obvious implementation of negative or white space. This type of negative space is usually not used very much in UX because it limits functionality. But that's where the beauty of it is, like in this wizard:
White space clearly defines the limited set of actions and tells the user what needs to be done (I admit this isn't the best example).
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There's a reason why Google has always been and most likely always will be a search bar with white space all around.
Other subtler uses of negative space in UX can include anything as simple as the space between the "share edit flag" section of your question and the "add comment" button. The comment functionality is isolated and highlighted by the white space around it, giving it more importance and puts it up higher in the visual hierarchy.
Negative space is everywhere in UX!