Your question really hinges on two things:
1. What level of exposure have your users had to the conventional schema (i.e., left-to-right)
2. Are you breaking your users' expectations by deviating from the norm.
The first point is probably most readily highlighted by the QWERTY vs. DVORAK keyboard problem. If you were to introduce a new user to a DVORAK keyboard then they'd assimilate the use of this more efficient tool for their purposes. However, introducing that same keyboard (without a QWERTY alternative) to an already established QWERTY user will result in, at best irritation and, at worst rejection.
It's not always about what is more naturally intuitive, most often it's about what the user is already familiar with. So while a user's language may be read right-to-left, their experience using particular tools (such as the command line) are likely to be firmly established as left-to-right.
So to the second point; know your target audience. Are they likely to have already assimilated a conventional (albeit initially alien) pattern or use, or are they likely to be unfamiliar with the environment you're delivering your product in and therefore likely to benefit from an adherence to an approach that mimics external patterns of familiarity?
Based on your citation of OS X, I'd assume that you're targeting users that are already being forced to accept the conventional pattern and you may risk more than you stand to gain by breaking that pattern.
Context is important.
