On a project, we show a list with checkboxes — and all options have some additional descriptions. So the question is should those descriptions be left aligned with the checkbox, or item title?
I like looking at these types of layouts as if they were bulleted lists with checkboxes for bullets.
See this example:
Benefits of exercise:
- Boosts mood
- Increases energy
- Improves sleep
- Helps control weight by elevating your metabolic rate, which allows you to burn more calories even when you're at rest.
- Enhances mental clarity by stimulating the release of chemicals in the brain that can improve memory, focus, and problem-solving skills.
As you can see, lists usually use this typographical pattern called hanging indent (or negative indent).
I think it'd help make your checkbox list read as both a list and selection options group and, more importantly, make it more scannable and easier to use. It also helps visually group description with the label, which is better too.
So overall, I usually go with the first option.