It would by very unexpected by the user that selection of "others" would deselect the previously selected options. Therefore it is necessary to make sure the user understands that it is either multiselect OR other.
You could achieve this by using a radio button with the options "select option" and "others" (naming of the to options should be as precise as possible). The selection of either radio button would change the next input field in either a multi select dropdown or a comment field.
And another thought about the multi select dropdown: if there are not to many options it is less complicated to the user if the options are visible instead of being hidden in a dropdown.