There are well known scanning patterns (such as F and Z scanning for websites that have been around for some time), but my assumption is that these have been built up over the years from research on single monitor usage studies or mobile device behavioural studies.
Also, there are studies (references required) to show that the scanning pattern is at least partly related to the type of website and the content displayed. This means that changing the design will have an impact on the scanning pattern (and vice versa).
However, the current trend in corporate environment is to have at least a dual monitor setup which is more complex because of the flexibility that it allows for users to customize their own views of the desktop space.
In addition, it is known that browser window sizes don't necessarily equate to the equivalent viewing space on single monitors, let alone dual screen setups (reference also required).
I am interested to know if there are scanning pattern studies for different viewport configurations?