Of course. Every interaction that involves enabling or assisting another can benefit from application of UX principles. Or it might be more accurate to say that there is nothing new in UX that hasn't already been done for ages in customer service, human factors engineering, technical communication, teaching, architecture, urban/parks planning, etc.
I'm forever reminding clients and readers that "Good usability is good customer service." We should not tolerate rude or unhelpful behavior from interfaces any more than we would from customer service staff. The analogies make great UX illustrations. For instance, if a customer were to fill out a form and miss one of the fields, and the clerk helping them tore the form up and handed them a new one, how long would that clerk last in your business? You'd either train them right quick, or fire them. But that kind of horrible customer service is still seen in some computer UIs (less so as time goes on, thankfully).
Here's a short blog post I wrote back in May, about an online shopping experience I had involving poor customer service.
There's another area, further afield, where I'm forever noticing the application of the same principles is in horse training. I'll not bore you with the details, but the idea is the same - that we are trying to guide another into a desired behavior. Suffice it to say, the idea "Make the right thing easy, and the wrong thing hard" has been around in horsemanship for longer than computers have been with us.
Great question, and one of my favorite subjects!