What kind of program has been used to produce this mock-up image?
As it currently stands, this question is not a good fit for our Q&A format. We expect answers to be supported by facts, references, or specific expertise, but this question will likely solicit debate, arguments, polling, or extended discussion. If you feel that this question can be improved and possibly reopened, see the FAQ for guidance.
I would have instantly said this was created using balsamiq.
Balsamiq is a wireframing mockup tool that you can use to design prototype interfaces using building block elements such as an empty browser window as a foundation and then gradually add finer grained components in order to produce a design.
You can also use Balsamiq to add drawings to your posts here in stack exchange.
Except... the yellow comment areas, I don't recognise them as being the balsamiq 'taped on' style of note - and to be honest, the lines look a little too straight and the search box is too straight as well.
I don't think this is balsamiq. There are quite a few similar tools for mockups / wireframes / prototypes, but if this was not created using one of those, then it was probably a drawing package rather than a paint package.
Even using a drawing package such as OmniGraffle, Adobe Illustrator, or Inkscape (free), a designer can produce and import their own snippets of elements in a similar fashion to the tailor-made tools.
Typically the popular prototyping tools tend to deliberately use lines that are not straight in order to promote a sketchy feel in order that clients etc do not focus on the detail, but on the overall design and layout.
The fact that the lines in this image are so straight, and the last column in the table does not have the emails aligned with the header, leads me to think this was probably not from a dedicated prototyping tool, but from the image alone, it's very hard to tell.
a bit longer answer than in my previous comment: the image is a wireframe, typically made with a Wireframing Tool or Mockup Tool such as Balsamiq (http://www.balsamiq.com/).
There's great variety of both free and commercial programs out there. Balsamiq is rather mid-range regarding the features and the prize.
Alternatives: AXURE (http://www.axure.com/) would be rather complex and that also shows in the price tag. OmniGraffle (http://www.omnigroup.com/products/omnigraffle/) less complex and more affordable.
Here's also a list of 10 free tools: http://mashable.com/2010/07/15/wireframing-tools/ but you'll find many more when you look for "mockup tools" or "wireframe tools".
You could however use any other drawing / graphics program to generate similar wireframe sketches.